Human Atheroma
نویسندگان
چکیده
منابع مشابه
Chemical shift magnetic resonance imaging of human atheroma.
Fifteen necropsy specimens of human descending aorta and from eight patients with atheromatous vascular disease were studied by magnetic resonance imaging at 0.5 T. Images were acquired in coronal and transverse planes to localised protruding lesions and then chemical shift imaging was performed by techniques described by Dixon and by Hinks. These techniques produce images in which signal stren...
متن کاملUptake of Plasmin-PN-1 Complexes in Early Human Atheroma
Zymogens are delivered to the arterial wall by radial transmural convection. Plasminogen can be activated within the arterial wall to produce plasmin, which is involved in evolution of the atherosclerotic plaque. Vascular smooth muscle cells (vSMCs) protect the vessels from proteolytic injury due to atherosclerosis development by highly expressing endocytic LDL receptor-related protein-1 (LRP-1...
متن کاملThe coagulant and thrombogenic properties of human atheroma.
SUMMARY Suspensions of gruel from severely atherosclerotic human aortas and coronary arteries were tested in several coagulation systems. The atheromatous material shortened the clotting time of normal whole blood and plasma and accelerated thrombus formation time in the Chandler apparatus. Normal human platelets in platelet-rich plasma were aggregated by the atheromatous gruel. Aggregation did...
متن کاملApoptotic death of inflammatory cells in human atheroma.
Although the accumulation of cholesterol and other lipidic material is unquestionably important in atherogenesis, the reasons why this material progressively accumulates, rather than being effectively cleared by phagocytic cells such as macrophages, are not completely understood. We hypothesize that atheromatous lesions may represent "death zones" that contain toxic materials such as oxysterols...
متن کاملMultimodal optoacoustic and multiphoton microscopy of human carotid atheroma
Carotid artery atherosclerosis is a main cause of stroke. Understanding atherosclerosis biology is critical in the development of targeted prevention and treatment strategies. Consequently, there is demand for advanced tools investigating atheroma pathology. We consider hybrid optoacoustic and multiphoton microscopy for the integrated and complementary interrogation of plaque tissue constituent...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1968
ISSN: 1351-0711
DOI: 10.1136/oem.25.2.158-a